Mechanisms of A-Type Lamin Targeting to Nuclear Ruptures Are Disrupted in LMNA- and BANF1-Associated Progerias

Mutations in the genes LMNA and BANF1 can lead to accelerated aging syndromes called progeria. The protein products of these genes, A-type lamins and BAF, respectively, are nuclear envelope (NE) proteins that interact and participate in various cellular processes, including nuclear envelope rupture...

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Detalles Bibliográficos
Autores principales: Sears, Rhiannon M., Roux, Kyle J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909658/
https://www.ncbi.nlm.nih.gov/pubmed/35269487
http://dx.doi.org/10.3390/cells11050865

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909658/
https://www.ncbi.nlm.nih.gov/pubmed/35269487
http://dx.doi.org/10.3390/cells11050865

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