TSPO Deficiency Exacerbates GSDMD-Mediated Macrophage Pyroptosis in Inflammatory Bowel Disease

Background: the 18-kDa translocator protein (TSPO) is a mitochondrial outer membrane protein, and its expression tends to increase in response to inflammatory stimulation, rapidly. However, the role of TSPO in inflammation and pyroptosis is not yet clear. Here, we identified TSPO as a novel key regu...

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Detalles Bibliográficos
Autores principales: Zhang, Xue, Han, Jingyi, Xu, Yi, Cai, Menghua, Gao, Fei, Han, Jiajia, Wang, Dongdong, Fu, Yi, Chen, Hui, He, Wei, Zhang, Jianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909696/
https://www.ncbi.nlm.nih.gov/pubmed/35269479
http://dx.doi.org/10.3390/cells11050856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909696/
https://www.ncbi.nlm.nih.gov/pubmed/35269479
http://dx.doi.org/10.3390/cells11050856

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