Cardiac Tissue-like 3D Microenvironment Enhances Route towards Human Fibroblast Direct Reprogramming into Induced Cardiomyocytes by microRNAs

The restoration of cardiac functionality after myocardial infarction represents a major clinical challenge. Recently, we found that transient transfection with microRNA combination (miRcombo: miR-1, miR-133, miR-208 and 499) is able to trigger direct reprogramming of adult human cardiac fibroblasts...

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Detalles Bibliográficos
Autores principales: Paoletti, Camilla, Marcello, Elena, Melis, Maria Luna, Divieto, Carla, Nurzynska, Daria, Chiono, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909733/
https://www.ncbi.nlm.nih.gov/pubmed/35269422
http://dx.doi.org/10.3390/cells11050800

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909733/
https://www.ncbi.nlm.nih.gov/pubmed/35269422
http://dx.doi.org/10.3390/cells11050800

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