Cargando…
Cardiac Tissue-like 3D Microenvironment Enhances Route towards Human Fibroblast Direct Reprogramming into Induced Cardiomyocytes by microRNAs
The restoration of cardiac functionality after myocardial infarction represents a major clinical challenge. Recently, we found that transient transfection with microRNA combination (miRcombo: miR-1, miR-133, miR-208 and 499) is able to trigger direct reprogramming of adult human cardiac fibroblasts...
Autores principales: | Paoletti, Camilla, Marcello, Elena, Melis, Maria Luna, Divieto, Carla, Nurzynska, Daria, Chiono, Valeria |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909733/ https://www.ncbi.nlm.nih.gov/pubmed/35269422 http://dx.doi.org/10.3390/cells11050800 |
Ejemplares similares
-
Impact of Biomaterials on Differentiation and Reprogramming Approaches for the Generation of Functional Cardiomyocytes
por: Paoletti, Camilla, et al.
Publicado: (2018) -
Bioengineering Methods in MicroRNA-Mediated Direct Reprogramming of Fibroblasts Into Cardiomyocytes
por: Paoletti, Camilla, et al.
Publicado: (2021) -
MicroRNA-Mediated Direct Reprogramming of Human Adult Fibroblasts Toward Cardiac Phenotype
por: Paoletti, C., et al.
Publicado: (2020) -
Tissue-engineered 3-dimensional (3D) microenvironment enhances the direct reprogramming of fibroblasts into cardiomyocytes by microRNAs
por: Li, Yanzhen, et al.
Publicado: (2016) -
Biomimetic design of bioartificial scaffolds for the in vitro modelling of human cardiac fibrosis
por: Spedicati, Mattia, et al.
Publicado: (2022)