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Current Understanding of Hypoxia in Glioblastoma Multiforme and Its Response to Immunotherapy

SIMPLE SUMMARY: Glioblastoma multiforme (GBM) is the most aggressive tumor type in the central nervous system. Hypoxia, defined as a lack of sufficient oxygen in tissues, is the most detrimental factor for the survival of GBM patients, promoting drug resistance, and invasion and inhibition of immune...

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Detalles Bibliográficos
Autores principales: Park, Jang Hyun, Lee, Heung Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909860/
https://www.ncbi.nlm.nih.gov/pubmed/35267480
http://dx.doi.org/10.3390/cancers14051176