Dual Effect of Combined Metformin and 2-Deoxy-D-Glucose Treatment on Mitochondrial Biogenesis and PD-L1 Expression in Triple-Negative Breast Cancer Cells

SIMPLE SUMMARY: Metformin and 2-deoxy-D-glucose are metabolic drugs with multiple and incompletely understood anti-cancer effects. Their combination can cause breast cancer cell detachment from the growth surface. Mitochondria are important for detached cell survival and metastasis, but how metformi...

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Detalles Bibliográficos
Autores principales: Repas, Jernej, Zupin, Mateja, Vodlan, Maja, Veranič, Peter, Gole, Boris, Potočnik, Uroš, Pavlin, Mojca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909901/
https://www.ncbi.nlm.nih.gov/pubmed/35267651
http://dx.doi.org/10.3390/cancers14051343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909901/
https://www.ncbi.nlm.nih.gov/pubmed/35267651
http://dx.doi.org/10.3390/cancers14051343

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