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Changes in Non-Deamidated versus Deamidated Epitope Targeting and Disease Prediction during the Antibody Response to Gliadin and Transglutaminase of Infants at Risk for Celiac Disease

Celiac disease (CeD) is a conditional autoimmune disorder with T cell-mediated immune response to gluten coupled with antibody production to gliadin and the self-protein tissue transglutaminase (TG2). TG2 contributes to the CeD pathomechanism by deamidating gliadin, thereby generating more immunogen...

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Detalles Bibliográficos
Autores principales: Diós, Ádám, Srinivasan, Bharani, Gyimesi, Judit, Werkstetter, Katharina, Valenta, Rudolf, Koletzko, Sibylle, Korponay-Szabó, Ilma R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909931/
https://www.ncbi.nlm.nih.gov/pubmed/35269639
http://dx.doi.org/10.3390/ijms23052498