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Modulation of Inflammatory Cytokine Production in Human Monocytes by cGMP and IRAK3

Interleukin-1 receptor-associated kinase-3 (IRAK3) is a critical checkpoint molecule of inflammatory responses in the innate immune system. The pseudokinase domain of IRAK3 contains a guanylate cyclase (GC) centre that generates small amounts of cyclic guanosine monophosphate (cGMP) associated with...

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Detalles Bibliográficos
Autores principales: Nguyen, Trang H., Axell, Anna, Turek, Ilona, Wright, Bree, Meehan-Andrews, Terri, Irving, Helen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909980/
https://www.ncbi.nlm.nih.gov/pubmed/35269704
http://dx.doi.org/10.3390/ijms23052552