Hexokinase 2 Inhibition and Biological Effects of BNBZ and Its Derivatives: The Influence of the Number and Arrangement of Hydroxyl Groups

Hexokinase 2 (HK2), an enzyme of the sugar kinase family, plays a dual role in glucose metabolism and mediating cancer cell apoptosis, making it an attractive target for cancer therapy. While positive HK2 expression usually promotes cancer cells survival, silencing or inhibiting this enzyme has been...

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Detalles Bibliográficos
Autores principales: Juszczak, Karolina, Kubicka, Anna, Kitel, Radosław, Dzido, Grzegorz, Łabieniec-Watała, Magdalena, Zawadzki, Serafin, Marczak, Agnieszka, Walczak, Krzysztof, Matczak, Karolina, Tomczyk, Mateusz D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910004/
https://www.ncbi.nlm.nih.gov/pubmed/35269760
http://dx.doi.org/10.3390/ijms23052616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910004/
https://www.ncbi.nlm.nih.gov/pubmed/35269760
http://dx.doi.org/10.3390/ijms23052616

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