Identification of Novel and Potent Indole-Based Benzenesulfonamides as Selective Human Carbonic Anhydrase II Inhibitors: Design, Synthesis, In Vitro, and In Silico Studies

In recent decades, human carbonic anhydrase inhibitors (hCAIs) have emerged as an important therapeutic class with various applications including antiglaucoma, anticonvulsants, and anticancer agents. Herein, a novel series of indole-based benzenesulfonamides were designed, synthesized, and biologica...

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Detalles Bibliográficos
Autores principales: Elkamhawy, Ahmed, Woo, Jiyu, Nada, Hossam, Angeli, Andrea, Bedair, Tarek M., Supuran, Claudiu T., Lee, Kyeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910009/
https://www.ncbi.nlm.nih.gov/pubmed/35269684
http://dx.doi.org/10.3390/ijms23052540

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910009/
https://www.ncbi.nlm.nih.gov/pubmed/35269684
http://dx.doi.org/10.3390/ijms23052540

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