Proximity Profiling of the CFTR Interaction Landscape in Response to Orkambi

Deletion of phenylalanine 508 (∆F508) of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) anion channel protein is the leading cause of Cystic Fibrosis (CF). Here, we report the analysis of CFTR and ∆F508-CFTR interactomes using BioID (proximity-dependent biotin identification), a tech...

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Detalles Bibliográficos
Autores principales: Iazzi, Melissa, Astori, Audrey, St-Germain, Jonathan, Raught, Brian, Gupta, Gagan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910062/
https://www.ncbi.nlm.nih.gov/pubmed/35269585
http://dx.doi.org/10.3390/ijms23052442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910062/
https://www.ncbi.nlm.nih.gov/pubmed/35269585
http://dx.doi.org/10.3390/ijms23052442

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