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Thiolated Hydroxypropyl-β-cyclodextrin: A Potential Multifunctional Excipient for Ocular Drug Delivery

The goal of this study was the design and evaluation of a thiolated cyclodextrin providing high drug solubilizing and mucoadhesive properties for ocular drug delivery. Hydroxypropyl-β-cyclodextrin (HP-β-CD) was thiolated via a microwave-assisted method, resulting in a degree of thiolation of 33%. Mu...

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Detalles Bibliográficos
Autores principales: Grassiri, Brunella, Knoll, Patrick, Fabiano, Angela, Piras, Anna Maria, Zambito, Ylenia, Bernkop-Schnürch, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910138/
https://www.ncbi.nlm.nih.gov/pubmed/35269753
http://dx.doi.org/10.3390/ijms23052612