The R369 Myosin Residue within Loop 4 Is Critical for Actin Binding and Muscle Function in Drosophila

The myosin molecular motor interacts with actin filaments in an ATP-dependent manner to yield muscle contraction. Myosin heavy chain residue R369 is located within loop 4 at the actin-tropomyosin interface of myosin’s upper 50 kDa subdomain. To probe the importance of R369, we introduced a histidine...

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Detalles Bibliográficos
Autores principales: Trujillo, Adriana S., Hsu, Karen H., Viswanathan, Meera C., Cammarato, Anthony, Bernstein, Sanford I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910226/
https://www.ncbi.nlm.nih.gov/pubmed/35269675
http://dx.doi.org/10.3390/ijms23052533

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910226/
https://www.ncbi.nlm.nih.gov/pubmed/35269675
http://dx.doi.org/10.3390/ijms23052533

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