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The R369 Myosin Residue within Loop 4 Is Critical for Actin Binding and Muscle Function in Drosophila
The myosin molecular motor interacts with actin filaments in an ATP-dependent manner to yield muscle contraction. Myosin heavy chain residue R369 is located within loop 4 at the actin-tropomyosin interface of myosin’s upper 50 kDa subdomain. To probe the importance of R369, we introduced a histidine...
Autores principales: | Trujillo, Adriana S., Hsu, Karen H., Viswanathan, Meera C., Cammarato, Anthony, Bernstein, Sanford I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910226/ https://www.ncbi.nlm.nih.gov/pubmed/35269675 http://dx.doi.org/10.3390/ijms23052533 |
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