Cargando…

Genetic Dissection of CRISPR-Cas9 Mediated Inheritance of Independently Targeted Alleles in Tobacco α-1,3-Fucosyltransferase 1 and β-1,2-Xylosyltransferase 1 Loci

We determined the specificity of mutations induced by the CRISPR-Cas9 gene-editing system in tobacco (Nicotiana benthamiana) alleles and subsequent genetic stability. For this, we prepared 248 mutant plants using an Agrobacterium-delivered CRISPR-Cas9 system targeting α-1,3-fucosyltransferase 1 (Fuc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Song, Hayoung, Ahn, Ju-Young, Yan, Fanzhuang, Ran, Yidong, Koo, Okjae, Lee, Geung-Joo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910323/ https://www.ncbi.nlm.nih.gov/pubmed/35269602 http://dx.doi.org/10.3390/ijms23052450

Ejemplares similares

Inactivation of the β(1,2)-xylosyltransferase and the α(1,3)-fucosyltransferase genes in Nicotiana tabacum BY-2 Cells by a Multiplex CRISPR/Cas9 Strategy Results in Glycoproteins without Plant-Specific Glycans
por: Mercx, Sébastien, et al.
Publicado: (2017)

Structural Basis for the Initiation of Glycosaminoglycan Biosynthesis by Human Xylosyltransferase 1
por: Briggs, David C., et al.
Publicado: (2018)

First Characterization of Human Dermal Fibroblasts Showing a Decreased Xylosyltransferase-I Expression Induced by the CRISPR/Cas9 System
por: Fischer, Bastian, et al.
Publicado: (2022)

Golgi fucosyltransferase 1 reveals its important role in α-1,4-fucose modification of N-glycan in CRISPR/Cas9 diatom Phaeodactylum tricornutum
por: Xie, Xihui, et al.
Publicado: (2023)

Identification of a new allele of O-fucosyltransferase 1 involved in Drosophila intestinal stem cell regulation
por: Shi, Lin, et al.
Publicado: (2021)

FUT8 Alpha-(1,6)-Fucosyltransferase in Cancer
por: Bastian, Kayla, et al.
Publicado: (2021)

α-1,6-Fucosyltransferase Is Essential for Myogenesis in Zebrafish
por: Hayashiji, Nozomi, et al.
Publicado: (2022)

Rapid generation of drug-resistance alleles at endogenous loci using CRISPR-Cas9 indel mutagenesis
por: Ipsaro, Jonathan J., et al.
Publicado: (2017)

Protein O-Fucosyltransferase 1 Undergoes Interdomain Flexibility in Solution
por: Lira-Navarrete, Erandi, et al.
Publicado: (2021)

The Eyelid Meibomian Gland Deficiency in Fucosyltransferase 1 Knockout Mice
por: Yoon, Chang Ho, et al.
Publicado: (2022)

Expression of xylosyltransferases I and II and their role in the pathogenesis of arthrofibrosis
por: Bernstein, Anke, et al.
Publicado: (2020)

Contributions of chaperone and glycosyltransferase activities of O-fucosyltransferase 1 to Notch signaling
por: Okajima, Tetsuya, et al.
Publicado: (2008)

Transcriptional Regulation of Fucosyltransferase 1 Gene Expression in Colon Cancer Cells
por: Taniuchi, Fumiko, et al.
Publicado: (2013)

Fucosyltransferase 1 and 2 play pivotal roles in breast cancer cells
por: Lai, Tai-Yu, et al.
Publicado: (2019)

Structural basis for substrate specificity and catalysis of α1,6-fucosyltransferase
por: García-García, Ana, et al.
Publicado: (2020)

First description of the complete human xylosyltransferase-I promoter region
por: Faust, Isabel, et al.
Publicado: (2014)

Silencing β1,2-xylosyltransferase in Transgenic Tomato Fruits Reveals xylose as Constitutive Component of Ige-Binding Epitopes
por: Paulus, Kathrin Elisabeth, et al.
Publicado: (2011)

Asparagine Tautomerization in Glycosyltransferase Catalysis. The Molecular Mechanism of Protein O-Fucosyltransferase 1
por: Piniello, Beatriz, et al.
Publicado: (2021)

Effect of Xylosyltransferase-I Silencing on Implanting Growth of Salivary Pleomorphic Adenoma
por: Ren, Guiyun, et al.
Publicado: (2018)

Human Xylosyltransferase I—An Important Linker between Acute Senescence and Fibrogenesis
por: Schmidt, Vanessa, et al.
Publicado: (2023)

CRISPR-Cas9 enables conditional mutagenesis of challenging loci
por: Schick, Joel A., et al.
Publicado: (2016)

Overexpression of α (1,6) fucosyltransferase in the development of castration-resistant prostate cancer cells
por: Höti, Naseruddin, et al.
Publicado: (2018)

microRNA-29b mediates fibrotic induction of human xylosyltransferase-I in human dermal fibroblasts via the Sp1 pathway
por: Riedel, Lara, et al.
Publicado: (2018)

Selective disruption of an oncogenic mutant allele by CRISPR/Cas9 induces efficient tumor regression
por: Koo, Taeyoung, et al.
Publicado: (2017)

Molecular cloning and characterization of a novel tomato xylosyltransferase specific for gentisic acid
por: Tárraga, Susana, et al.
Publicado: (2010)

Xylosyltransferase-I Regulates Glycosaminoglycan Synthesis during the Pathogenic Process of Human Osteoarthritis
por: Venkatesan, Narayanan, et al.
Publicado: (2012)

The Impact of Inflammatory Stimuli on Xylosyltransferase-I Regulation in Primary Human Dermal Fibroblasts
por: Ly, Thanh-Diep, et al.
Publicado: (2022)

The Human Myofibroblast Marker Xylosyltransferase-I: A New Indicator for Macrophage Polarization
por: Ly, Thanh-Diep, et al.
Publicado: (2022)

Targeted assemblies of cas1 suggest CRISPR-Cas’s response to soil warming
por: Wu, Ruonan, et al.
Publicado: (2020)

Transcriptional activation of fucosyltransferase (FUT) genes using the CRISPR-dCas9-VPR technology reveals potent N-glycome alterations in colorectal cancer cells
por: Blanas, Athanasios, et al.
Publicado: (2018)

Super-Mendelian inheritance mediated by CRISPR/Cas9 in the female mouse germline
por: Grunwald, Hannah A., et al.
Publicado: (2019)

CRISPR/Cas9-based Engineering of Immunoglobulin Loci in Hybridoma Cells
por: Gall, Camille Le M., et al.
Publicado: (2023)

c-Fos mediates α1, 2-fucosyltransferase 1 and Lewis y expression in response to TGF-β1 in ovarian cancer
por: Hao, Yingying, et al.
Publicado: (2017)

CRISPR/Cas9‐mediated tetra‐allelic mutation of the ‘Green Revolution’ SEMIDWARF‐1 (SD‐1) gene confers lodging resistance in tef (Eragrostis tef)
por: Beyene, Getu, et al.
Publicado: (2022)

Fucosyltransferase 1 mediates angiogenesis, cell adhesion and rheumatoid arthritis synovial tissue fibroblast proliferation
por: Isozaki, Takeo, et al.
Publicado: (2014)

CRISPR/Cas9 Editing of the Mutant Huntingtin Allele In Vitro and In Vivo
por: Monteys, Alex Mas, et al.
Publicado: (2017)

Allosteric regulation in CRISPR/Cas1-Cas2 protospacer acquisition mediated by DNA and Cas2
por: Long, Chunhong, et al.
Publicado: (2021)

Target-dependent nickase activities of CRISPR-Cas nucleases Cpf1 and Cas9
por: Hua Fu, Becky Xu, et al.
Publicado: (2019)

Real-time Observation of CRISPR spacer acquisition by Cas1–Cas2 integrase
por: Budhathoki, Jagat B., et al.
Publicado: (2020)

CRISPR-Cas13a Inhibits HIV-1 Infection
por: Yin, Lijuan, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_oks440l7oa2fivhvfjil1uipkg