Conformational Dynamics of the Soluble and Membrane-Bound Forms of Interleukin-1 Receptor Type-1: Insights into Linker Flexibility and Domain Orientation

Interleukin-1 receptor type 1 (IL-1R1) is a key player in inflammation and immune responses. This receptor regulates IL-1 activity in two forms: as a membrane-bound form and as a soluble ectodomain. The details and differences between the conformational dynamics of the membrane-bound and the soluble...

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Detalles Bibliográficos
Autores principales: Luís, João P., Mata, Ana I., Simões, Carlos J. V., Brito, Rui M. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910350/
https://www.ncbi.nlm.nih.gov/pubmed/35269739
http://dx.doi.org/10.3390/ijms23052599

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910350/
https://www.ncbi.nlm.nih.gov/pubmed/35269739
http://dx.doi.org/10.3390/ijms23052599

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