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Identification of Neoantigens in Cancer Cells as Targets for Immunotherapy

The clinical benefits of immune checkpoint blockage (ICB) therapy have been widely reported. In patients with cancer, researchers have demonstrated the clinical potential of antitumor cytotoxic T cells that can be reinvigorated or enhanced by ICB. Compared to self-antigens, neoantigens derived from...

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Detalles Bibliográficos
Autores principales: Okada, Masahiro, Shimizu, Kanako, Fujii, Shin-ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910406/
https://www.ncbi.nlm.nih.gov/pubmed/35269735
http://dx.doi.org/10.3390/ijms23052594