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JAK2-Mediated Phosphorylation of Stress-Induced Phosphoprotein-1 (STIP1) in Human Cells

Stress-induced phosphoprotein-1 (STIP1)—a heat shock protein (HSP)70/HSP90 adaptor protein—is commonly overexpressed in malignant cells, where it controls proliferation via multiple signaling pathways, including JAK2/STAT3. We have previously shown that STIP1 stabilizes the protein tyrosine kinase J...

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Detalles Bibliográficos
Autores principales: Chao, Angel, Liao, Min-Jie, Chen, Shun-Hua, Lee, Yun-Shien, Tsai, Chi-Neu, Lin, Chiao-Yun, Tsai, Chia-Lung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910420/
https://www.ncbi.nlm.nih.gov/pubmed/35269562
http://dx.doi.org/10.3390/ijms23052420