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Reorienting Mechanism of Harderoheme in Coproheme Decarboxylase—A Computational Study

Coproheme decarboxylase (ChdC) is an important enzyme in the coproporphyrin-dependent pathway (CPD) of Gram-positive bacteria that decarboxylates coproheme on two propionates at position 2 and position 4 sequentially to generate heme b by using H(2)O(2) as an oxidant. This work focused on the ChdC f...

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Detalles Bibliográficos
Autores principales: Liu, Wei, Pang, Yunjie, Song, Yutian, Li, Xichen, Tan, Hongwei, Chen, Guangju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910490/
https://www.ncbi.nlm.nih.gov/pubmed/35269706
http://dx.doi.org/10.3390/ijms23052564