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Reorienting Mechanism of Harderoheme in Coproheme Decarboxylase—A Computational Study
Coproheme decarboxylase (ChdC) is an important enzyme in the coproporphyrin-dependent pathway (CPD) of Gram-positive bacteria that decarboxylates coproheme on two propionates at position 2 and position 4 sequentially to generate heme b by using H(2)O(2) as an oxidant. This work focused on the ChdC f...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910490/ https://www.ncbi.nlm.nih.gov/pubmed/35269706 http://dx.doi.org/10.3390/ijms23052564 |