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Histone Deacetylase Inhibitors Downregulate Calcium Pyrophosphate Crystal Formation in Human Articular Chondrocytes

Calcium pyrophosphate (CPP) deposition disease (CPPD) is a form of CPP crystal-induced arthritis. A high concentration of extracellular pyrophosphate (ePPi) in synovial fluid is positively correlated with the formation of CPP crystals, and ePPi can be upregulated by ankylosis human (ANKH) and ectonu...

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Detalles Bibliográficos
Autores principales: Chang, Chi-Ching, Lee, Kun-Lin, Chan, Tze-Sian, Chung, Chia-Chen, Liang, Yu-Chih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910507/
https://www.ncbi.nlm.nih.gov/pubmed/35269745
http://dx.doi.org/10.3390/ijms23052604