An Efficient Way to Screen Inhibitors of Energy-Coupling Factor (ECF) Transporters in a Bacterial Uptake Assay

Herein, we report a novel whole-cell screening assay using Lactobacillus casei as a model microorganism to identify inhibitors of energy-coupling factor (ECF) transporters. This promising and underexplored target may have important pharmacological potential through modulation of vitamin homeostasis...

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Detalles Bibliográficos
Autores principales: Bousis, Spyridon, Winkler, Steffen, Haupenthal, Jörg, Fulco, Francesco, Diamanti, Eleonora, Hirsch, Anna K. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910649/
https://www.ncbi.nlm.nih.gov/pubmed/35269783
http://dx.doi.org/10.3390/ijms23052637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910649/
https://www.ncbi.nlm.nih.gov/pubmed/35269783
http://dx.doi.org/10.3390/ijms23052637

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