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An Efficient Way to Screen Inhibitors of Energy-Coupling Factor (ECF) Transporters in a Bacterial Uptake Assay
Herein, we report a novel whole-cell screening assay using Lactobacillus casei as a model microorganism to identify inhibitors of energy-coupling factor (ECF) transporters. This promising and underexplored target may have important pharmacological potential through modulation of vitamin homeostasis...
Autores principales: | Bousis, Spyridon, Winkler, Steffen, Haupenthal, Jörg, Fulco, Francesco, Diamanti, Eleonora, Hirsch, Anna K. H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910649/ https://www.ncbi.nlm.nih.gov/pubmed/35269783 http://dx.doi.org/10.3390/ijms23052637 |
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