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Potential of a Novel Chemical Compound Targeting Matrix Metalloprotease-13 for Early Osteoarthritis: An In Vitro Study

Osteoarthritis is a progressive disease characterized by cartilage destruction in the joints. Matrix metalloproteinases (MMPs) and a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTSs) play key roles in osteoarthritis progression. In this study, we screened a chemical compound lib...

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Detalles Bibliográficos
Autores principales: Inagaki, Junko, Nakano, Airi, Hatipoglu, Omer Faruk, Ooka, Yuka, Tani, Yurina, Miki, Akane, Ikemura, Kentaro, Opoku, Gabriel, Ando, Ryosuke, Kodama, Shintaro, Ohtsuki, Takashi, Yamaji, Hirosuke, Yamamoto, Shusei, Katsuyama, Eri, Watanabe, Shogo, Hirohata, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910651/
https://www.ncbi.nlm.nih.gov/pubmed/35269821
http://dx.doi.org/10.3390/ijms23052681