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Potential of a Novel Chemical Compound Targeting Matrix Metalloprotease-13 for Early Osteoarthritis: An In Vitro Study
Osteoarthritis is a progressive disease characterized by cartilage destruction in the joints. Matrix metalloproteinases (MMPs) and a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTSs) play key roles in osteoarthritis progression. In this study, we screened a chemical compound lib...
Autores principales: | Inagaki, Junko, Nakano, Airi, Hatipoglu, Omer Faruk, Ooka, Yuka, Tani, Yurina, Miki, Akane, Ikemura, Kentaro, Opoku, Gabriel, Ando, Ryosuke, Kodama, Shintaro, Ohtsuki, Takashi, Yamaji, Hirosuke, Yamamoto, Shusei, Katsuyama, Eri, Watanabe, Shogo, Hirohata, Satoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910651/ https://www.ncbi.nlm.nih.gov/pubmed/35269821 http://dx.doi.org/10.3390/ijms23052681 |
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