The Platelet Collagen Receptor GPVI Is Cleaved by Tspan15/ADAM10 and Tspan33/ADAM10 Molecular Scissors

The platelet-activating collagen receptor GPVI represents the focus of clinical trials as an antiplatelet target for arterial thrombosis, and soluble GPVI is a plasma biomarker for several human diseases. A disintegrin and metalloproteinase 10 (ADAM10) acts as a ‘molecular scissor’ that cleaves the...

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Detalles Bibliográficos
Autores principales: Koo, Chek Ziu, Matthews, Alexandra L., Harrison, Neale, Szyroka, Justyna, Nieswandt, Bernhard, Gardiner, Elizabeth E., Poulter, Natalie S., Tomlinson, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910667/
https://www.ncbi.nlm.nih.gov/pubmed/35269584
http://dx.doi.org/10.3390/ijms23052440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910667/
https://www.ncbi.nlm.nih.gov/pubmed/35269584
http://dx.doi.org/10.3390/ijms23052440

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