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Monitoring TRPC7 Conformational Changes by BRET Following GPCR Activation

Transient receptor potential canonical (TRPC) channels are membrane proteins involved in regulating Ca(2+) homeostasis, and whose functions are modulated by G protein-coupled receptors (GPCR). In this study, we developed bioluminescent resonance energy transfer (BRET) biosensors to better study chan...

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Detalles Bibliográficos
Autores principales: Pétigny, Cécile, Dumont, Audrey-Ann, Giguère, Hugo, Collette, Audrey, Holleran, Brian J., Iftinca, Mircea, Altier, Christophe, Besserer-Offroy, Élie, Auger-Messier, Mannix, Leduc, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910688/
https://www.ncbi.nlm.nih.gov/pubmed/35269644
http://dx.doi.org/10.3390/ijms23052502