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Development of VPC-70619, a Small-Molecule N-Myc Inhibitor as a Potential Therapy for Neuroendocrine Prostate Cancer

The Myc family of transcription factors are involved in the development and progression of numerous cancers, including prostate cancer (PCa). Under the pressure of androgen receptor (AR)-directed therapies resistance can occur, leading to the lethal form of PCa known as neuroendocrine prostate cance...

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Detalles Bibliográficos
Autores principales: Ton, Anh-Tien, Foo, Jane, Singh, Kriti, Lee, Joseph, Kalyta, Anastasia, Morin, Helene, Perez, Carl, Ban, Fuqiang, Leblanc, Eric, Lallous, Nada, Cherkasov, Artem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910697/
https://www.ncbi.nlm.nih.gov/pubmed/35269731
http://dx.doi.org/10.3390/ijms23052588