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A Hybrid Machine Learning and Network Analysis Approach Reveals Two Parkinson’s Disease Subtypes from 115 RNA-Seq Post-Mortem Brain Samples

Precision medicine emphasizes fine-grained diagnostics, taking individual variability into account to enhance treatment effectiveness. Parkinson’s disease (PD) heterogeneity among individuals proves the existence of disease subtypes, so subgrouping patients is vital for better understanding disease...

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Detalles Bibliográficos
Autores principales: Termine, Andrea, Fabrizio, Carlo, Strafella, Claudia, Caputo, Valerio, Petrosini, Laura, Caltagirone, Carlo, Cascella, Raffaella, Giardina, Emiliano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910747/
https://www.ncbi.nlm.nih.gov/pubmed/35269707
http://dx.doi.org/10.3390/ijms23052557