β–Lactam TRPM8 Antagonist RGM8-51 Displays Antinociceptive Activity in Different Animal Models

Transient receptor potential melastatin subtype 8 (TRPM8) is a cation channel extensively expressed in sensory neurons and implicated in different painful states. However, the effectiveness of TRPM8 modulators for pain relief is still a matter of discussion, since structurally diverse modulators lea...

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Detalles Bibliográficos
Autores principales: Martín-Escura, Cristina, Medina-Peris, Alicia, Spear, Luke A., de la Torre Martínez, Roberto, Olivos-Oré, Luis A., Barahona, María Victoria, González-Rodríguez, Sara, Fernández-Ballester, Gregorio, Fernández-Carvajal, Asia, Artalejo, Antonio R., Ferrer-Montiel, Antonio, González-Muñiz, Rosario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910920/
https://www.ncbi.nlm.nih.gov/pubmed/35269831
http://dx.doi.org/10.3390/ijms23052692

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910920/
https://www.ncbi.nlm.nih.gov/pubmed/35269831
http://dx.doi.org/10.3390/ijms23052692

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