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PD-1/PD-L1 Immuno-Mediated Therapy in NAFLD: Advantages and Obstacles in the Treatment of Advanced Disease

Non-alcoholic fatty liver disease (NAFLD) is characterized by an enhanced activation of the immune system, which predispose the evolution to nonalcoholic steatohepatitis (NASH) and hepatocellular carcinoma (HCC). Resident macrophages and leukocytes exert a key role in the pathogenesis of NAFLD. In p...

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Detalles Bibliográficos
Autores principales: Lombardi, Rosa, Piciotti, Roberto, Dongiovanni, Paola, Meroni, Marica, Fargion, Silvia, Fracanzani, Anna Ludovica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910930/
https://www.ncbi.nlm.nih.gov/pubmed/35269846
http://dx.doi.org/10.3390/ijms23052707