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Spliced or Unspliced, That Is the Question: The Biological Roles of XBP1 Isoforms in Pathophysiology
X-box binding protein 1 (XBP1) is a member of the CREB/ATF basic region leucine zipper family transcribed as the unspliced isoform (XBP1-u), which, upon exposure to endoplasmic reticulum stress, is spliced into its spliced isoform (XBP1-s). XBP1-s interacts with the cAMP response element of major hi...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910952/ https://www.ncbi.nlm.nih.gov/pubmed/35269888 http://dx.doi.org/10.3390/ijms23052746 |