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Spliced or Unspliced, That Is the Question: The Biological Roles of XBP1 Isoforms in Pathophysiology

X-box binding protein 1 (XBP1) is a member of the CREB/ATF basic region leucine zipper family transcribed as the unspliced isoform (XBP1-u), which, upon exposure to endoplasmic reticulum stress, is spliced into its spliced isoform (XBP1-s). XBP1-s interacts with the cAMP response element of major hi...

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Detalles Bibliográficos
Autores principales:	Luo, Xinxin, Alfason, Leader, Wei, Mankun, Wu, Shourong, Kasim, Vivi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910952/ https://www.ncbi.nlm.nih.gov/pubmed/35269888 http://dx.doi.org/10.3390/ijms23052746

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