Mechanism Underlying the Bypass of Apurinic/Pyrimidinic Site Analogs by Sulfolobus acidocaldarius DNA Polymerase IV

The spontaneous depurination of genomic DNA occurs frequently and generates apurinic/pyrimidinic (AP) site damage that is mutagenic or lethal to cells. Error-prone DNA polymerases are specifically responsible for the translesion synthesis (TLS) of specific DNA damage, such as AP site damage, general...

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Detalles Bibliográficos
Autores principales: Huang, Qin-Ying, Song, Dong, Wang, Wei-Wei, Peng, Li, Chen, Hai-Feng, Xiao, Xiang, Liu, Xi-Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910976/
https://www.ncbi.nlm.nih.gov/pubmed/35269871
http://dx.doi.org/10.3390/ijms23052729

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910976/
https://www.ncbi.nlm.nih.gov/pubmed/35269871
http://dx.doi.org/10.3390/ijms23052729

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