Identification of a Tumor Cell Associated Type I IFN Resistance Gene Expression Signature of Human Melanoma, the Components of Which Have a Predictive Potential for Immunotherapy

We developed a human melanoma model using the HT168-M1 cell line to induce IFN-α2 resistance in vitro (HT168-M1res), which was proven to be maintained in vivo in SCID mice. Comparing the mRNA profile of in vitro cultured HT168-M1res cells to its sensitive counterpart, we found 79 differentially expr...

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Detalles Bibliográficos
Autores principales: Ladányi, Andrea, Rásó, Erzsébet, Barbai, Tamás, Vízkeleti, Laura, Puskás, László G., Kovács, Szonja A., Győrffy, Balázs, Tímár, József
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911010/
https://www.ncbi.nlm.nih.gov/pubmed/35269844
http://dx.doi.org/10.3390/ijms23052704

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911010/
https://www.ncbi.nlm.nih.gov/pubmed/35269844
http://dx.doi.org/10.3390/ijms23052704

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