Novel Design of Neuropeptide-Based Drugs with β-Sheet Breaking Potential in Amyloid-Beta Cascade: Molecular and Structural Deciphers

Our work discusses the investigation of 75 peptide-based drugs with the potential ability to break the β-sheet structures of amyloid-beta peptides from senile plaques. Hence, this study offers a unique insight into the design of neuropeptide-based drugs with β-sheet breaker potential in the amyloid-...

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Detalles Bibliográficos
Autores principales: Mocanu, Cosmin Stefan, Niculaua, Marius, Zbancioc, Gheorghita, Mangalagiu, Violeta, Drochioiu, Gabi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911100/
https://www.ncbi.nlm.nih.gov/pubmed/35269999
http://dx.doi.org/10.3390/ijms23052857

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911100/
https://www.ncbi.nlm.nih.gov/pubmed/35269999
http://dx.doi.org/10.3390/ijms23052857

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