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Bone Mass and Osteoblast Activity Are Sex-Dependent in Mice Lacking the Estrogen Receptor α in Chondrocytes and Osteoblast Progenitor Cells

While estrogen receptor alpha (ERα) is known to be important for bone development and homeostasis, its exact function during osteoblast differentiation remains unclear. Conditional deletion of ERα during specific stages of osteoblast differentiation revealed different bone phenotypes, which were als...

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Detalles Bibliográficos
Autores principales: Steppe, Lena, Bülow, Jasmin, Tuckermann, Jan, Ignatius, Anita, Haffner-Luntzer, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911122/
https://www.ncbi.nlm.nih.gov/pubmed/35270044
http://dx.doi.org/10.3390/ijms23052902