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Hyperglycemia Promotes Endothelial Cell Senescence through AQR/PLAU Signaling Axis

Hyperglycemia is reported to accelerate endothelial cell senescence that contributes to diabetic complications. The underlying mechanism, however, remains elusive. We previously demonstrated AQR as a susceptibility gene for type 2 diabetes mellitus (T2DM) and showed that it was increased in multiple...

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Detalles Bibliográficos
Autores principales: Wan, Yiqi, Liu, Zhirui, Wu, Andong, Khan, Abdul Haseeb, Zhu, Ying, Ding, Shuangjin, Li, Xueer, Zhao, Ya, Dai, Ximo, Zhou, Jin, Liu, Jiankun, Li, Yuanyuan, Gong, Xueting, Liu, Man, Tian, Xiao-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911151/
https://www.ncbi.nlm.nih.gov/pubmed/35270021
http://dx.doi.org/10.3390/ijms23052879