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Human MicroRNAs Attenuate the Expression of Immediate Early Proteins and HCMV Replication during Lytic and Latent Infection in Connection with Enhancement of Phosphorylated RelA/p65 (Serine 536) That Binds to MIEP

Attenuating the expression of immediate early (IE) proteins is essential for controlling the lytic replication of human cytomegalovirus (HCMV). The human microRNAs (hsa-miRs), miR-200b-3p and miR-200c-3p, have been identified to bind the 3′-untranslated region (3′-UTR) of the mRNA encoding IE protei...

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Detalles Bibliográficos
Autores principales: Hong, Yeon-Mi, Min, Seo Yeon, Kim, Dayeong, Kim, Subin, Seo, Daekwan, Lee, Kyoung Hwa, Han, Sang Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911160/
https://www.ncbi.nlm.nih.gov/pubmed/35269913
http://dx.doi.org/10.3390/ijms23052769