Free Cholesterol Accelerates Aβ Self-Assembly on Membranes at Physiological Concentration

The effects of membranes on the early-stage aggregation of amyloid β (Aβ) have come to light as potential mechanisms by which neurotoxic species are formed in Alzheimer’s disease. We have shown that direct Aβ-membrane interactions dramatically enhance the Aβ aggregation, allowing for oligomer assemb...

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Detalles Bibliográficos
Autores principales: Hashemi, Mohtadin, Banerjee, Siddhartha, Lyubchenko, Yuri L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911190/
https://www.ncbi.nlm.nih.gov/pubmed/35269945
http://dx.doi.org/10.3390/ijms23052803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911190/
https://www.ncbi.nlm.nih.gov/pubmed/35269945
http://dx.doi.org/10.3390/ijms23052803

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