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Free Cholesterol Accelerates Aβ Self-Assembly on Membranes at Physiological Concentration
The effects of membranes on the early-stage aggregation of amyloid β (Aβ) have come to light as potential mechanisms by which neurotoxic species are formed in Alzheimer’s disease. We have shown that direct Aβ-membrane interactions dramatically enhance the Aβ aggregation, allowing for oligomer assemb...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911190/ https://www.ncbi.nlm.nih.gov/pubmed/35269945 http://dx.doi.org/10.3390/ijms23052803 |