Conformational Stabilization of Gp41-Mimetic Miniproteins Opens Up New Ways of Inhibiting HIV-1 Fusion

Inhibition of the HIV-1 fusion process constitutes a promising strategy to neutralize the virus at an early stage before it enters the cell. In this process, the envelope glycoprotein (Env) plays a central role by promoting membrane fusion. We previously identified a vulnerability at the flexible C-...

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Detalles Bibliográficos
Autores principales: Cano-Muñoz, Mario, Lucas, Julie, Lin, Li-Yun, Cesaro, Samuele, Moog, Christiane, Conejero-Lara, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911282/
https://www.ncbi.nlm.nih.gov/pubmed/35269936
http://dx.doi.org/10.3390/ijms23052794

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911282/
https://www.ncbi.nlm.nih.gov/pubmed/35269936
http://dx.doi.org/10.3390/ijms23052794

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