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Efficacy of Flotetuzumab in Combination with Cytarabine in Patient-Derived Xenograft Models of Pediatric Acute Myeloid Leukemia

Children with acute myeloid leukemia (AML) have a poor prognosis despite the intensification of chemotherapy. Future efforts to improve outcomes should focus on more precise targeting of leukemia cells. CD123, or IL3RA, is expressed on the surface of nearly all pediatric AML samples and is a high-pr...

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Detalles Bibliográficos
Autores principales: Barwe, Sonali P., Kisielewski, Anne, Bonvini, Ezio, Muth, John, Davidson-Moncada, Jan, Kolb, Edward Anders, Gopalakrishnapillai, Anilkumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911345/
https://www.ncbi.nlm.nih.gov/pubmed/35268423
http://dx.doi.org/10.3390/jcm11051333