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Efficacy of Flotetuzumab in Combination with Cytarabine in Patient-Derived Xenograft Models of Pediatric Acute Myeloid Leukemia
Children with acute myeloid leukemia (AML) have a poor prognosis despite the intensification of chemotherapy. Future efforts to improve outcomes should focus on more precise targeting of leukemia cells. CD123, or IL3RA, is expressed on the surface of nearly all pediatric AML samples and is a high-pr...
Autores principales: | Barwe, Sonali P., Kisielewski, Anne, Bonvini, Ezio, Muth, John, Davidson-Moncada, Jan, Kolb, Edward Anders, Gopalakrishnapillai, Anilkumar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911345/ https://www.ncbi.nlm.nih.gov/pubmed/35268423 http://dx.doi.org/10.3390/jcm11051333 |
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