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Antioxidant Effects of Statins by Modulating Nrf2 and Nrf2/HO-1 Signaling in Different Diseases

Statins are competitive inhibitors of hydroxymethylglutaryl-CoA (HMG-CoA) reductase and have been used to treat elevated low-density lipoprotein cholesterol (LDL-C) for almost four decades. Antioxidant and anti-inflammatory properties which are independent of the lipid-lowering effects of statins, i...

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Detalles Bibliográficos
Autores principales: Mansouri, Atena, Reiner, Željko, Ruscica, Massimiliano, Tedeschi-Reiner, Eugenia, Radbakhsh, Shabnam, Bagheri Ekta, Mariam, Sahebkar, Amirhossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911353/
https://www.ncbi.nlm.nih.gov/pubmed/35268403
http://dx.doi.org/10.3390/jcm11051313