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Sodium Nitroprusside-Induced Activation of Vascular Smooth Muscle BK Channels Is Mediated by PKG Rather Than by a Direct Interaction with NO

Nitric oxide (NO) is a powerful vasodilator in different vascular beds and NO-donors are widely used in clinical practice. Early data suggested that NO and NO-donors activate vascular smooth muscle high-conductance, calcium-activated potassium channels (BK channels). There exist two hypotheses expla...

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Detalles Bibliográficos
Autores principales: Gagov, Hristo, Gribkova, Irina V., Serebryakov, Vladimir N., Schubert, Rudolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911362/
https://www.ncbi.nlm.nih.gov/pubmed/35269940
http://dx.doi.org/10.3390/ijms23052798