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The Role of Glycogen Synthase Kinase-3 in the Regulation of Ribosome Biogenesis in Rat Soleus Muscle under Disuse Conditions

It is well-established that prolonged exposure to real or simulated microgravity/disuse conditions results in a significant reduction in the rate of muscle protein synthesis (PS) and loss of muscle mass. Muscle protein synthesis is largely dependent upon translational capacity (ribosome content), th...

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Detalles Bibliográficos
Autores principales: Rozhkov, Sergey V., Sharlo, Kristina A., Shenkman, Boris S., Mirzoev, Timur M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911371/
https://www.ncbi.nlm.nih.gov/pubmed/35269893
http://dx.doi.org/10.3390/ijms23052751