Myocardial GRK2 Reduces Fatty Acid Metabolism and β-Adrenergic Receptor-Mediated Mitochondrial Responses

G-protein coupled receptor (GPCR) kinase 2 (GRK2) is upregulated in heart failure (HF) patients and mouse models of cardiac disease. GRK2 is a regulator of β-adrenergic receptors (βARs), a GPCR involved in ionotropic and chronotropic responses. We and others have recently reported GRK2 to be localiz...

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Detalles Bibliográficos
Autores principales: Zhai, Ruxu, Varner, Erika L., Rao, Ajay, Karhadkar, Sunil, Di Carlo, Antonio, Snyder, Nathaniel W., Sato, Priscila Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911442/
https://www.ncbi.nlm.nih.gov/pubmed/35269919
http://dx.doi.org/10.3390/ijms23052777

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911442/
https://www.ncbi.nlm.nih.gov/pubmed/35269919
http://dx.doi.org/10.3390/ijms23052777

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