Early Inactivation of Membrane Estrogen Receptor Alpha (ERα) Recapitulates the Endothelial Dysfunction of Aged Mouse Resistance Arteries

Flow-mediated dilation (FMD) of resistance arteries is essential for tissue perfusion but it decreases with ageing. As estrogen receptor alpha (Erα encoded by Esr1), and more precisely membrane ERα, plays an important role in FMD in young mice in a ligand-independent fashion, we evaluated its influe...

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Detalles Bibliográficos
Autores principales: Favre, Julie, Vessieres, Emilie, Guihot, Anne-Laure, Grimaud, Linda, Proux, Coralyne, Loufrani, Laurent, Lenfant, Françoise, Fontaine, Coralie, Arnal, Jean-François, Henrion, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911509/
https://www.ncbi.nlm.nih.gov/pubmed/35270003
http://dx.doi.org/10.3390/ijms23052862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911509/
https://www.ncbi.nlm.nih.gov/pubmed/35270003
http://dx.doi.org/10.3390/ijms23052862

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