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Quantification of Venetoclax for Therapeutic Drug Monitoring in Chinese Acute Myeloid Leukemia Patients by a Validated UPLC-MS/MS Method

Venetoclax has emerged as a breakthrough for treatment of leukemia with a wide interindividual variability in pharmacokinetics. Herein, a rapid, sensitive, and reliable UPLC-MS/MS method for quantification of venetoclax in plasma was developed and validated. The method was operated in the multiple-r...

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Detalles Bibliográficos
Autores principales: Yang, Xi, Mei, Chen, He, Xiaoying, He, Lingjuan, Lu, Xiaoyang, Tong, Hongyan, Lou, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911561/
https://www.ncbi.nlm.nih.gov/pubmed/35268708
http://dx.doi.org/10.3390/molecules27051607